AAPS Journal期刊信息与投稿指南 AAPS J 影响因子： 3.4 JCR分区： Q2 新锐分区： 医学3区 是否综述期刊： N/A 是否预警： 不在预警名单内 是否OA： 否 出版国家/地区： UNITED STATES 出版社： Springer International Publishing 发刊时间： 1999 收录数据库： SCIE/Scopus收录 ISSN：1550-7416 期刊介绍 The AAPS Journal, an official journal of the American Association of Pharmaceutical Scientists (AAPS), publishes novel and significant findings in the various areas of pharmaceutical sciences impacting human and veterinary therapeutics, including: · Drug Design and Discovery · Pharmaceutical Biotechnology · Biopharmaceutics, Formulation, and Drug Delivery · Metabolism and Transport · Pharmacokinetics, Pharmacodynamics, and Pharmacometrics · Translational Research · Clinical Evaluations and Therapeutic Outcomes · Regulatory Science We invite submissions under the following article types: · Original Research Articles · Reviews and Mini-reviews · White Papers, Commentaries, and Editorials · Meeting Reports · Brief/Technical Reports and Rapid Communications · Regulatory Notes · Tutorials · Protocols in the Pharmaceutical Sciences In addition, The AAPS Journal publishes themes, organized by guest editors, which are focused on particular areas of current interest to our field. AAPS期刊是美国药学科学家协会（AAPS）的官方期刊，发表影响人类和兽医治疗的药学科学各个领域的新颖和重要发现，包括：·药物设计和发现·药物生物技术·生物药剂学、制剂和药物递送·代谢和转运·药代动力学、药效学和药理学·转化研究·临床评价和治疗结果·监管科学我们邀请以下文章类型的投稿：·原创研究文章·综述和小型综述·白色、评论和社论·会议报告·简报/技术报告和快速交流·监管说明·教程·药学科学方案此外，AAPS期刊还发布由客座编辑组织的主题，这些主题集中在我们领域当前感兴趣的特定领域。 年发文量 168 国人发稿量 5.04 国人发文占比 0.03% 自引率 8.8% 平均录取率 - 平均审稿周期 约1.0个月 数据非官方，来自网友分享经验 版面费 - 偏重研究方向 医学-药学 期刊官网 https://www.springer.com/12248 投稿链接 https://www.editorialmanager.com/aapsj 期刊高被引文献 Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0298-x Report of the AAPS Guidance Forum on the FDA Draft Guidance for Industry: “Drug Products, Including Biological Products, that Contain Nanomaterials” 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0329-7 A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0350-x PBPK Absorption Modeling: Establishing the In Vitro–In Vivo Link—Industry Perspective 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0292-3 Translational Quantitative Systems Pharmacology in Drug Development: from Current Landscape to Good Practices 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0339-5 In Vitro and In Vivo Co-delivery of siRNA and Doxorubicin by Folate-PEG-Appended Dendrimer/Glucuronylglucosyl-β-Cyclodextrin Conjugate 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0327-9 Fit-for-Purpose Quality Control System in Continuous Bioanalysis During Long-Term Pediatric Studies 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0375-1 Incurred Sample Reanalysis: Time to Change the Sample Size Calculation? 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0293-2 Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0334-x Compensated Hydroxyl Radical Protein Footprinting Measures Buffer and Excipient Effects on Conformation and Aggregation in an Adalimumab Biosimilar 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0358-2 Nanomaterial-Based Modulation of Tumor Microenvironments for Enhancing Chemo/Immunotherapy 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0333-y Anthocyanin Delphinidin Prevents Neoplastic Transformation of Mouse Skin JB6 P+ Cells: Epigenetic Re-activation of Nrf2-ARE Pathway 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0355-5 “Development of Fixed Dose Combination Products” Workshop Report: Considerations of Gastrointestinal Physiology and Overall Development Strategy 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0346-6 Estimation of Solid Tumor Doubling Times from Progression-Free Survival Plots Using a Novel Statistical Approach 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0302-5 A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0390-2 Theoretical Considerations for Direct Translation of Unbound Liver-to-Plasma Partition Coefficient from In Vitro to In Vivo 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0314-1 Evaluating a Multiscale Mechanistic Model of the Immune System to Predict Human Immunogenicity for a Biotherapeutic in Phase 1 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0361-7 Mind the Gaps: Ontogeny of Human Brain P-gp and Its Impact on Drug Toxicity 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0340-z Quality Controls in Ligand Binding Assays: Recommendations and Best Practices for Preparation, Qualification, Maintenance of Lot to Lot Consistency, and Prevention of Assay Drift 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0354-6 On the Comparison of Methods in Analyzing Bounded Outcome Score Data 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0370-6 Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0295-0 TCPro: an In Silico Risk Assessment Tool for Biotherapeutic Protein Immunogenicity 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0368-0 Biotransformation of the New Synthetic Cannabinoid with an Alkene, MDMB-4en-PINACA, by Human Hepatocytes, Human Liver Microsomes, and Human Urine and Blood 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0381-3 Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biological Half-Life 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0377-z CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0322-1 A Fit-for-Purpose Method for the Detection of Human Antibodies to Surface-Exposed Components of BMS-986263, a Lipid Nanoparticle-Based Drug Product Containing a siRNA Drug Substance 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0360-8 Fetal Concentrations of Budesonide and Fluticasone Propionate: a Study in Mice 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0313-2 Neutralizing Antibody Assay Development with High Drug and Target Tolerance to Support Clinical Development of an Anti-TFPI Therapeutic Monoclonal Antibody 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0320-3 In Vitro Metabolism and Hepatic Intrinsic Clearance of the Synthetic Cannabinoid Receptor Agonist JWH-122 and Its Four ω-Halogenated Analogues 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0338-6 Population Pharmacokinetics and Pharmacodynamics of Apixaban Linking Its Plasma Concentration to Intrinsic Activated Coagulation Factor X Activity in Japanese Patients with Atrial Fibrillation 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0353-7 Modeling Combined Anti-Inflammatory Effects of Dexamethasone and Tofacitinib in Arthritic Rats 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0362-6 Deconvolution Analysis by Non-linear Regression Using a Convolution-Based Model: Comparison of Nonparametric and Parametric Approaches 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0389-8 Anti-drug Antibody Assay Validation: Improved Reporting of the Assay Selectivity via Simpler Positive Control Recovery Data Analysis 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0347-5 Phase-Appropriate Application of Analytical Methods to Monitor Subvisible Particles Across the Biotherapeutic Drug Product Life Cycle 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0384-0 Mechanistic Deconvolution of Oral Absorption Model with Dynamic Gastrointestinal Fluid to Predict Regional Rate and Extent of GI Drug Dissolution 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0385-z Quantitative Prediction of Human Hepatic Clearance for P450 and Non-P450 Substrates from In Vivo Monkey Pharmacokinetics Study and In Vitro Metabolic Stability Tests Using Hepatocytes 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0294-1 Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0305-2 Estimating In Vivo Fractional Contribution of OATP1B1 to Human Hepatic Active Uptake by Mechanistically Modeling Pharmacogenetic Data 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0337-7 Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0309-y Inhibition of Hepatic CYP2D6 by the Active N-Oxide Metabolite of Sorafenib 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0374-2 Current Perspectives on Ligand-Binding Assay Practices in the Quantification of Circulating Therapeutic Proteins for Biosimilar Biological Product Development 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0397-8 Multiplexed Gene Expression as a Characterization of Bioactivity for Interferon Beta (IFN-β) Biosimilar Candidates: Impact of Innate Immune Response Modulating Impurities (IIRMIs) 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0300-7 Dissolution Chamber for Small Drug Delivery System in the Periodontal Pocket 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0317-y Correction to: A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART® 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0348-4 Variability Attribution for Automated Model Building 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0310-5 Systemic Bioequivalence Is Unlikely to Equal Target Site Bioequivalence for Nanotechnology Oncologic Products 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0296-z A Novel Method for Analysing Frequent Observations from Questionnaires in Order to Model Patient-Reported Outcomes: Application to EXACT® Daily Diary Data from COPD Patients 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0319-9 Population Pharmacokinetic Modeling in the Presence of Missing Time-Dependent Covariates: Impact of Body Weight on Pharmacokinetics of Paracetamol in Neonates 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0331-0 Analysis of the Regulatory Divergence of Comparative Dissolution Requirements for Post-Approval Manufacturing Changes of Modified Release Solid Oral Dosage Forms 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0383-1 Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXaI16L in Preclinical Species 来源期刊：The AAPS Journal DOI：10.1208/s12248-019-0324-z 查看更多 质量指标占比 研究类文章占比 OA被引用占比 撤稿占比 出版后修正文章占比 88.69% 37.2% - - 相关指数 影响因子 影响因子 年发文量 自引率 Cite Score 预警情况 查看说明 时间 预警情况 2026年03月发布的新锐学术版 不在预警名单中 2025年03月发布的2025版 不在预警名单中 2024年02月发布的2024版 不在预警名单中 2023年01月发布的2023版 不在预警名单中 2021年12月发布的2021版 不在预警名单中 2020年12月发布的2020版 不在预警名单中 * 来源：中科院《 国际期刊预警名单》 JCR分区 WOS分区等级： 2区 版本 按学科 分区 WOS期刊SCI分区 WOS期刊SCI分区 WOS期刊SCI分区是指SCI官方（Web of Science）为每个学科内的期刊按照IF数值排 序，将期刊按照四等分的方法划分的Q1-Q4等级，Q1代表质量最高，即常说的1区期刊。 （2024-2025年最新版） PHARMACOLOGY & 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